The city's historic center is characterized by narrow winding streets, whitewashed buildings adorned with colorful flower pots, and bustling squares filled with cafes and restaurants. Here, visitors can explore historical landmarks such as the Castle of San Marcos, an ancient fortress that now serves as a museum, and the Bullring, which hosts bullfighting events during the summer.

Puerto de Santa María is also renowned for its sherry wine production. It is home to several bodegas (wineries) where visitors can take guided tours to learn about the winemaking process and sample a variety of local wines, including the famous sherry. The city celebrates its wine heritage with festivals and events dedicated to the local viticulture.